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FMO3--TMAO axis modulates the clinical outcome in chronic heart-failure patients with reduced ejection

Frontiers of Medicine 2022, Volume 16, Issue 2, Pages 295-305 doi: 10.1007/s11684-021-0857-2

Abstract: tertile of plasma TMAO was associated with a significant increment in hazard ratio (HR) for the composite outcomeThus, higher plasma TMAO levels indicated increased risk of the composite outcome of cardiovascular death

Keywords： chronic heart failure trimethylamine-N-oxide flavin monooxygenase 3 single nucleotide polymorphism

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Challenges and opportunities in improving left ventricular remodelling and clinical outcome following

Frontiers of Medicine 2021, Volume 15, Issue 3, Pages 416-437 doi: 10.1007/s11684-021-0852-7

Abstract: with individualised management of hypertension and atrial fibrillation is likely to improve patient outcomepara-valvular aortic regurgitation along with therapy of angiotensin receptor blockade will improve patient outcome

Keywords： surgical aortic valve replacement trans-catheter aortic valve implantation left ventricular hypertrophy and fibrosis myocardial force-velocity relationship His-Purkinje pacing renin-angiotensin system inhibitors coronary access impairment

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Poor adherence to P2Y12 antagonists increased cardiovascular risks in Chinese PCI-treated patients

Yang Sun,Chenze Li,Lina Zhang,Dong Hu,Xudong Zhang,Ting Yu,Min Tao,Dao Wen Wang,Xiaoqing Shen

Frontiers of Medicine 2017, Volume 11, Issue 1, Pages 53-61 doi: 10.1007/s11684-017-0502-2

Abstract: prevention medications (ATM) of patients after acute coronary syndrome (ACS) is associated with poor clinical

Keywords： acute coronary syndromes adherence to secondary prevention medications clinical outcome

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Fertility outcome analysis after modified laparoscopic microsurgical tubal anastomosis

Jihui Ai, Pei Zhang, Lei Jin, Yufeng Li, Jing Yue, Ding Ma, Hanwang Zhang

Frontiers of Medicine 2011, Volume 5, Issue 3, Pages 310-314 doi: 10.1007/s11684-011-0152-8

Abstract: The current study aims to evaluate the fertility outcome after modified laparoscopic microsurgical tubalunderwent modified laparoscopic microsurgical tubal anastomosis were monitored to investigate the fertility outcome

Keywords： modified laparoscopy tubal anastomosis microsurgery

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A Predictive Nomogram for Predicting Improved Clinical Outcome Probability in Patients with COVID-19 Article

Jiaojiao Xie, Ding Shi, Mingyang Bao, Xiaoyi Hu, Wenrui Wu, Jifang Sheng, Kaijin Xu, Qing Wang, Jingjing Wu, Kaicen Wang, Daiqiong Fang, Yating Li, Lanjuan Li

Engineering 2022, Volume 8, Issue 1, Pages 122-129 doi: 10.1016/j.eng.2020.05.014

Abstract: Clinical information and laboratory findings were collected and compared between the outcomes of improvedin the multivariate logistics regression model were used to select prognostic factors for predicting clinicalThere were numerous differences in clinical characteristics and laboratory findings between patientsideal model on the calibration plot and was clinically practical according to the decision curve and clinicalThe nomogram we constructed is useful for clinicians to predict improved clinical outcome probability

Keywords： Coronavirus disease 2019 (COVID-19) Nomogram Patient-relevant outcome

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Artificial intelligence in radiotherapy: a technological review

Ke Sheng

Frontiers of Medicine 2020, Volume 14, Issue 4, Pages 431-449 doi: 10.1007/s11684-020-0761-1

Abstract: the RT workflow and identifies areas, including imaging, treatment planning, quality assurance, and outcome

Keywords： artificial intelligence radiation therapy medical imaging treatment planning quality assurance outcome

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Core Outcome Set for Clinical Trials on Coronavirus Disease 2019 (COS-COVID) Article

Xinyao Jin, Bo Pang, Junhua Zhang, Qingquan Liu, Zhongqi Yang, Jihong Feng, Xuezheng Liu, Lei Zhang, Baohe Wang, Yuhong Huang, Alice Josephine Fauci, Yuling Ma, Myeong Soo Lee, Wei’an Yuan, Yanming Xie, Jianyuan Tang, Rui Gao, Liang Du, Shuo Zhang, Hanmei Qi, Yu Sun, Wenke Zheng, Fengwen Yang, Huizi Chua, Keyi Wang, Yi Ou, Ming Huang, Yan Zhu, Jiajie Yu, Jinhui Tian, Min Zhao, Jingqing Hu, Chen Yao, Youping Li, Boli Zhang

Engineering 2020, Volume 6, Issue 10, Pages 1147-1152 doi: 10.1016/j.eng.2020.03.002

Abstract:

Since its outbreak in December 2019, a series of clinical trials on coronavirus disease 2019 (COVIDThis study aimed to develop a core outcome set (COS) for clinical trials on COVID-19 in order to tacklethe outcome issues.clinical trial protocols and outcomes in order to form an outcome pool.The COS-COVID is currently the most valuable and practical clinical outcome set for the evaluation of

Keywords： Novel coronavirus pneumonia Core outcome set COVID-19 2019-nCoV Coronavirus disease Clinical trials

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Ontological reconstruction of the clinical terminology of traditional Chinese medicine

Li Ma,Baoyan Liu,Qi Xie,Shusong Mao,Zhiwei Cui

Frontiers of Medicine 2014, Volume 8, Issue 3, Pages 358-361 doi: 10.1007/s11684-014-0348-9

Abstract:

This study proposes the ontological reconstruction of the current clinical terminology of traditionalof preliminary work related to the said reconstruction, including the ontology-based analysis of TCM clinicalWe conclude that the ontological reconstruction of TCM clinical terminology provides a proper translation

Keywords： ontology traditional Chinese medicine clinical terminology

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The clinical impact of tricuspid regurgitation in patients with a biatrial orthotopic heart transplant

Frontiers of Medicine 2023, Volume 17, Issue 3, Pages 527-533 doi: 10.1007/s11684-022-0967-5

Abstract: In this study, we aim to elucidate the clinical impact and long-term course of tricuspid regurgitation

Keywords： orthotopic heart transplant tricuspid regurgitation clinical impact biatrial heart transplantation

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Tianhua Xu, Zitong Sheng, Li Yao

Frontiers of Medicine 2017, Volume 11, Issue 3, Pages 340-348 doi: 10.1007/s11684-017-0570-3

Abstract: A slow increase of subnephrotic proteinuria (<3.5 g/d) is the most common clinical manifestation of

Keywords： obesity-related glomerulopathy pathogenesis pathologic clinical characteristics

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Coronavirus disease 2019 (COVID-19): a clinical update

Min Zhou, Xinxin Zhang, Jieming Qu

Frontiers of Medicine 2020, Volume 14, Issue 2, Pages 126-135 doi: 10.1007/s11684-020-0767-8

Abstract: promising antivirals, convalescent plasma transfusion, and tocilizumab needs to be investigated by ongoing clinical

Keywords： coronavirus disease 2019 epidemiology pathology radiology clinical characteristics treatment

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Hypertension in patients with CKD in China: clinical characteristics and management

Guangyan Cai, Xiangmei Chen

Frontiers of Medicine 2017, Volume 11, Issue 3, Pages 307-309 doi: 10.1007/s11684-017-0578-8

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Bone metastasis of hepatocellular carcinoma: facts and hopes from clinical and translational perspectives

Frontiers of Medicine 2022, Volume 16, Issue 4, Pages 551-573 doi: 10.1007/s11684-022-0928-z

Abstract: Patients with hepatocellular carcinoma (HCC) and bone metastasis (BM) suffer from greatly reduced life quality and a dismal prognosis. However, BM in HCC has long been overlooked possibly due to its relatively low prevalence in previous decades. To date, no consensus or guidelines have been reached or formulated for the prevention and management of HCC BM. Our narrative review manifests the increasing incidence of HCC BM to sound the alarm for additional attention. The risk factors, diagnosis, prognosis, and therapeutic approaches of HCC BM are detailed to provide a panoramic view of this disease to clinicians and specialists. We further delineate an informative cancer bone metastatic cascade based on evidence from recent studies and point out the main factors responsible for the tumor-associated disruption of bone homeostasis and the formation of skeletal cancer lesions. We also present the advances in the pathological and molecular mechanisms of HCC BM to shed light on translational opportunities. Dilemmas and challenges in the treatment and investigation of HCC BM are outlined and discussed to encourage further endeavors in the exploration of underlying pathogenic and molecular mechanisms, as well as the development of novel effective therapies for HCC patients with BM.

Keywords： HCC bone osteotropism clinical basic researches advances

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Heterogeneity of the tumor immune microenvironment and clinical interventions

Frontiers of Medicine 2023, Volume 17, Issue 4, Pages 617-648 doi: 10.1007/s11684-023-1015-9

Abstract: Heterogeneity of the tumor immune microenvironment and clinical interventions

Keywords： Heterogeneity tumor immune

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Pathogen evolution, prevention/control strategy and clinical features of COVID-19: experiences from China

Frontiers of Medicine doi: 10.1007/s11684-023-1043-5

Abstract: The overall clinical features of variants of concern (VOC), heterogeneity in the clinical manifestations

Keywords： coronavirus disease 2019 SARS-CoV-2 epidemiology clinical features

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Title Author Date Type Operation

FMO3--TMAO axis modulates the clinical outcome in chronic heart-failure patients with reduced ejection

Journal Article

Challenges and opportunities in improving left ventricular remodelling and clinical outcome following

Journal Article

Poor adherence to P2Y12 antagonists increased cardiovascular risks in Chinese PCI-treated patients

Yang Sun,Chenze Li,Lina Zhang,Dong Hu,Xudong Zhang,Ting Yu,Min Tao,Dao Wen Wang,Xiaoqing Shen

Journal Article

Fertility outcome analysis after modified laparoscopic microsurgical tubal anastomosis

Jihui Ai, Pei Zhang, Lei Jin, Yufeng Li, Jing Yue, Ding Ma, Hanwang Zhang

Journal Article

A Predictive Nomogram for Predicting Improved Clinical Outcome Probability in Patients with COVID-19

Jiaojiao Xie, Ding Shi, Mingyang Bao, Xiaoyi Hu, Wenrui Wu, Jifang Sheng, Kaijin Xu, Qing Wang, Jingjing Wu, Kaicen Wang, Daiqiong Fang, Yating Li, Lanjuan Li

Journal Article

Artificial intelligence in radiotherapy: a technological review

Ke Sheng

Journal Article

Core Outcome Set for Clinical Trials on Coronavirus Disease 2019 (COS-COVID)

Journal Article

Ontological reconstruction of the clinical terminology of traditional Chinese medicine

Li Ma,Baoyan Liu,Qi Xie,Shusong Mao,Zhiwei Cui

Journal Article

The clinical impact of tricuspid regurgitation in patients with a biatrial orthotopic heart transplant

Journal Article

Obesity-related glomerulopathy: pathogenesis, pathologic, clinical characteristics and treatment